Irish-bred De Sica tagged favored Ramonti in the final strides to win Sunday's Derby Italiano (Ity-I) by a head at Capannelle.
Ramonti tired after the leading the field throughout the 1 1/2-mile test for 3-year-olds, giving in close to home. Ramonti had beaten De Sica handily in the Italian Two Thousand Guineas last month.
Emilio Borromeo, who bred, owns and trains the winning son of Sri Pekan, said he plans to transfer the bay colt to Luca Cumani for a possible try at Newmarket this summer.
Marco Monteriso kept De Sica close to the leader while racing fourth in the early going, switching left two furlongs from the wire for the winning charge. Jane's Park, the third-place finisher, was also driving in a tight finish. Jane's Park wound up three-quarters of a length behind the winner. Urgente finished fourth, just a head farther back.
The final time was 2:28.6 on a good to firm course. Fifteen ran.